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| Single-Season Wins Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Wins | IP | Year | Career Leaderboard |
| 1. | Juan Eames | 20 | 214.0 | 2006 | |
| Jose Davalos | 20 | 214.0 | 2006 | ||
| 3. | Robert Unrein | 19 | 237.0 | 2006 | |
| Lawrence Rosol | 19 | 227.0 | 2006 | ||
| Richard Fumihiro | 19 | 240.3 | 2005 | ||
| Robert Unrein | 19 | 239.3 | 2005 | ||
| Samuel Scull | 19 | 232.7 | 2005 | ||
| 8. | Michael Nock | 18 | 194.3 | 2006 | |
| 9. | Robert Haire | 17 | 239.0 | 2006 | |
| Anthony Calderon | 17 | 234.3 | 2006 | ||
| Takitarou Bunrakuken | 17 | 219.0 | 2006 | ||
| Lionel Slater | 17 | 212.3 | 2006 | ||
| Samuel Grullon | 17 | 256.3 | 2005 | ||
| Clair Johnson | 17 | 246.7 | 2005 | ||
| Thomas Borton | 17 | 235.7 | 2005 | ||
| Sadayoshi Yachi | 17 | 201.0 | 2005 | ||
| 17. | Alvaro Santana | 16 | 193.7 | 2006 | |
| Chris West | 16 | 191.7 | 2006 | ||
| Ronny Boyle | 16 | 256.3 | 2005 | ||
| Bernardo Reynoso | 16 | 256.0 | 2005 | ||
| Bill Poteet | 16 | 233.3 | 2005 | ||
| Ruben Campbell | 16 | 233.0 | 2005 | ||
| Freddy Berenguer | 16 | 199.7 | 2005 | ||
| 24. | Bernardo Reynoso | 15 | 241.7 | 2006 | |
| Clair Johnson | 15 | 241.0 | 2006 | ||
| Stanford Hinton | 15 | 238.3 | 2006 | ||
| Archie Aubry | 15 | 228.0 | 2006 | ||
| Brian Sisemore | 15 | 220.7 | 2006 | ||
| Antonio Manrique | 15 | 213.3 | 2006 | ||
| Joseph Orman | 15 | 204.7 | 2006 | ||
| Kevin Grant | 15 | 196.0 | 2006 | ||
| Robert Haire | 15 | 242.7 | 2005 | ||
| Lionel Slater | 15 | 221.7 | 2005 | ||
| Anthony Chou | 15 | 212.3 | 2005 | ||
| Robert Danielson | 15 | 210.3 | 2005 | ||
| Michael Nock | 15 | 203.0 | 2005 | ||
| Kenneth Vanburen | 15 | 202.7 | 2005 | ||
| Bret McHugh | 15 | 189.3 | 2005 | ||
| Joseph Seldon | 15 | 164.7 | 2005 | ||
| 40. | Samuel Scull | 14 | 230.0 | 2006 | |
| Robert Danielson | 14 | 222.0 | 2006 | ||
| Julio Lozoya | 14 | 218.7 | 2006 | ||
| Mario Benero | 14 | 218.3 | 2006 | ||
| Pablo Bustos | 14 | 211.0 | 2006 | ||
| Johnny Coniglio | 14 | 206.3 | 2006 | ||
| Alberto Castillo | 14 | 203.7 | 2006 | ||
| Jared Motoichi | 14 | 197.0 | 2006 | ||
| Archie Aubry | 14 | 247.0 | 2005 | ||
| Don Martin | 14 | 243.7 | 2005 | ||
| Richard Coburn | 14 | 231.7 | 2005 | ||
| Stanley Terrell | 14 | 231.7 | 2005 | ||
| John Principato | 14 | 228.7 | 2005 | ||
| Estanis Delmonte | 14 | 223.7 | 2005 | ||
| Takitarou Bunrakuken | 14 | 217.0 | 2005 | ||
| Daren Crook | 14 | 212.7 | 2005 | ||
| Leon Santana | 14 | 211.7 | 2005 | ||
| Juan Eames | 14 | 208.0 | 2005 | ||
| Numbers Hight | 14 | 201.0 | 2005 | ||
| Mario Benero | 14 | 200.3 | 2005 | ||
| Walter Heatherly | 14 | 167.0 | 2005 | ||
| 61. | Freddy Berenguer | 13 | 230.0 | 2006 | |
| Hershel Dayton | 13 | 226.0 | 2006 | ||
| Devin Bostwick | 13 | 221.3 | 2006 | ||
| John Principato | 13 | 207.7 | 2006 | ||
| Victor Proctor | 13 | 207.3 | 2006 | ||
| Charles Hitch | 13 | 206.3 | 2006 | ||
| Tokuichirou Kenzo | 13 | 202.7 | 2006 | ||
| Derek Bradfield | 13 | 202.3 | 2006 | ||
| Estanis Delmonte | 13 | 196.0 | 2006 | ||
| Juan McDade | 13 | 193.3 | 2006 | ||
| Justin Munford | 13 | 192.7 | 2006 | ||
| Troy Lindell | 13 | 190.3 | 2006 | ||
| Tomas Bonet | 13 | 175.3 | 2006 | ||
| Ken Newman | 13 | 168.0 | 2006 | ||
| Dave Dones | 13 | 162.3 | 2006 | ||
| Richard Grigg | 13 | 150.3 | 2006 | ||
| Tokuichirou Kenzo | 13 | 239.7 | 2005 | ||
| Jared Motoichi | 13 | 232.0 | 2005 | ||
| Arthur Myricks | 13 | 231.3 | 2005 | ||
| Bill Ybarra | 13 | 223.7 | 2005 | ||
| Juan Puņal | 13 | 219.3 | 2005 | ||
| Filiberto Navarro | 13 | 208.0 | 2005 | ||
| Amadeo Martinez | 13 | 207.7 | 2005 | ||
| Patricio Aguiar | 13 | 206.3 | 2005 | ||
| David Zeman | 13 | 197.7 | 2005 | ||
| Andres Llamas | 13 | 174.3 | 2005 | ||
| 87. | Richard Coburn | 12 | 236.3 | 2006 | |
| Jonathan Silverstein | 12 | 199.7 | 2006 | ||
| Leslie Zapata | 12 | 198.3 | 2006 | ||
| Ruben Campbell | 12 | 194.7 | 2006 | ||
| Douglas Drumm | 12 | 172.7 | 2006 | ||
| Jonathan Caton | 12 | 128.3 | 2006 | ||
| Anthony Calderon | 12 | 255.7 | 2005 | ||
| Brian Sisemore | 12 | 238.7 | 2005 | ||
| Lawrence Rosol | 12 | 225.0 | 2005 | ||
| Rauru Kiyonobu | 12 | 219.3 | 2005 | ||
| Vernon Hessler | 12 | 215.0 | 2005 | ||
| Jeffery Paton | 12 | 204.0 | 2005 | ||
| Alfredo Gracia | 12 | 202.0 | 2005 | ||
| Antonio Manrique | 12 | 199.7 | 2005 |
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